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PC2002 - Molecular Basis of Therapeutics 3

Credit points: 3
Year: 2014
Student Contribution Band: Band 2
Administered by:

Available to students enrolled in the Bachelor of Pharmacy.

This subject builds upon the fundamental concepts of pharmacology and medicinal chemistry introduced in the first year of the Pharmacy program. It deals with the concepts of pharmacokinetics, including the mechanisms of drug metabolism and excretion. The subject also introduces the basic principles of toxicology. The importance of chemical analysis in relation to drug development, forensic science, drug testing and clinical diagnosis is examined. Specific topics to be covered include instrumental methods of analysis and structure determination (particularly NMR, chromatographic separation techniques (HPLC and GLC, thermal analysis methods (DSC and TGA) and Vibrational Spectroscopic techniques (FTIR and Raman spectroscopy) and X-ray powder diffraction. Approaches to the development of new pharmaceutical agents, including pharmacognosy, rational drug design and high-throughput screening are also introduced.

Learning Outcomes

  • current approaches to the development of new pharmaceutical agents, including rational drug design, drug screening and natural product pharmacology;
  • the basic principles of toxicology, including the role of the liver in drug and xenobiotic transformation;
  • the manner in which drugs are handled by the body (pharmacokinetics), including the mechanisms of drug metabolism and excretion;
  • the role of chemical analysis in drug development, forensic science, drug testing and clinical diagnosis.
Prerequisites: CH1001 and PC1005
Inadmissible
Subject
Combinations:
PP3150

Availabilities

Townsville, Internal, Study Period 1
Census Date 27-Mar-2014
Coordinator: Dr Ioana Bowden
Lecturers: Dr Chris Glasson, Assoc. Professor Michael Oelgemoeller, Dr George Vamvounis, Assoc. Professor Bruce Bowden, Dr Ioana Bowden.
Workload expectations:
  • 36 hours lectures
  • 3 hours tutorials
  • 12 hours practicals
Assessment: end of semester exam (70%); laboratory performance and reports (30%).

Note: Minor variations might occur due to the continuous Subject quality improvement process, and in case of minor variation(s) in assessment details, the Subject Outline represents the latest official information.