PC1005 - Molecular Basis of Therapeutics 1
|Student Contribution Band:
Available to students enrolled in the Bachelor of Pharmacy.
The following content (~36 lectures) is common with CH1002. Physical Chemistry.
What controls reaction rates? - Reactions, kinetics and mechanism. Electrochemistry
- fundamentals and applications in industry and nature. Phase equilibria, colligative
properties and chemical partitioning applied to environmental, industrial, physiological
and biological process. Organic Chemistry. General features of organic reactions,
reactive intermediates, energetics. Mechanisms and applications of major reaction
types including relevant biological examples: radical substitution, electrophilic
addition, nucleophilic substitution at saturated carbon. nucleophilic addition and
substitution at carbonyl goups. Conjugation, resonance and aromaticity. Electrophilic
aromatic substitution. Spectroscopy and structure determination. Chemistry in nature
and industry, chemical manufacturing and cycling of elements through the environment.
Systematic chemistry of selected groups of the Periodic Table. Aspects of the chemistry
of the transition metals including their role in biological systems.
- develop competence in the application of common laboratory techniques in chemistry,
particularly those relevant to the measurement of drug structure and activity;
- in conjunction with Ch1001, to provide the background in key chemical concepts and
principles necessary for appropriate understanding of the pharmaceutics, medicinal
chemistry and pharmacology subjects in later years of the course.
Study Period 2
|Census Date 28-Aug-2014
||Assoc. Professor Michael Oelgemoeller
||Dr Chris Glasson, Assoc. Professor Michael Oelgemoeller, Dr George Vamvounis, Professor Peter Junk.
- 39 hours lectures
- 12 hours tutorials
- 30 hours practicals
||end of semester exam (60%); assignments (10%); laboratory work and reports (30%).
Minor variations might occur due to the continuous Subject quality improvement process,
and in case
of minor variation(s) in assessment details, the Subject Outline represents the latest