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PC1005 - Molecular Basis of Therapeutics 1

Credit points: 3
Year: 2014
Student Contribution Band: Band 2
Administered by:

Available to students enrolled in the Bachelor of Pharmacy.

The following content (~36 lectures) is common with CH1002. Physical Chemistry. What controls reaction rates? - Reactions, kinetics and mechanism. Electrochemistry - fundamentals and applications in industry and nature. Phase equilibria, colligative properties and chemical partitioning applied to environmental, industrial, physiological and biological process. Organic Chemistry. General features of organic reactions, reactive intermediates, energetics. Mechanisms and applications of major reaction types including relevant biological examples: radical substitution, electrophilic addition, nucleophilic substitution at saturated carbon. nucleophilic addition and substitution at carbonyl goups. Conjugation, resonance and aromaticity. Electrophilic aromatic substitution. Spectroscopy and structure determination. Chemistry in nature and industry, chemical manufacturing and cycling of elements through the environment. Systematic chemistry of selected groups of the Periodic Table. Aspects of the chemistry of the transition metals including their role in biological systems.

Learning Outcomes

  • develop competence in the application of common laboratory techniques in chemistry, particularly those relevant to the measurement of drug structure and activity;
  • in conjunction with Ch1001, to provide the background in key chemical concepts and principles necessary for appropriate understanding of the pharmaceutics, medicinal chemistry and pharmacology subjects in later years of the course.
Prerequisites: CH1001


Townsville, Internal, Study Period 2
Census Date 28-Aug-2014
Coordinator: Assoc. Professor Michael Oelgemoeller
Lecturers: Dr Chris Glasson, Assoc. Professor Michael Oelgemoeller, Dr George Vamvounis, Professor Peter Junk.
Workload expectations:
  • 39 hours lectures
  • 12 hours tutorials
  • 30 hours practicals
Assessment: end of semester exam (60%); assignments (10%); laboratory work and reports (30%).

Note: Minor variations might occur due to the continuous Subject quality improvement process, and in case of minor variation(s) in assessment details, the Subject Outline represents the latest official information.