PC1005 - Molecular Basis of Therapeutics 1
|Student Contribution Band:
||College of Science and Engineering
Available to students enrolled in the Bachelor of Pharmacy.
This subject (37 lectures) is in common with CH1002 and builds on the content of CH1001
to provide broad exposure of students to the major principles and reactions of relevance
to inorganic, organic and physical chemistry. A major emphasis will continue to be
the applicability of chemistry in the wider scientific context, particularly in the
biological, biomedical, earth and environmental sciences. Organic Chemistry (13
lectures): General features of organic reactions, reactive intermediates and energetics.
Mechanisms and applications of major reaction types: radical substitution, electrophilic
addition, nucleophilic substitution at saturated carbon, nucleophilic addition and
substitution at carbonyl groups. Electrophilic aromatic substitution. Stereochemistry
of hydrocarbons. Spectroscopy and structure determination. Physical Chemistry (12
lectures): What controls reaction rates? Reactions, kinetics and mechanism. Electrochemistry.
Fundamentals and applications in industry and nature. Phase equilibria, colligative
properties and chemical partitioning applied to environmental, industrial, physiological
and biological process. Atomic structure, Bonding and Periodicity (12 lectures):
Applications of redox chemistry in industrial processes, an introduction to transition
metal chemistry and its involvement in bioinorganic chemistry, spectroscopy with applications
in analytical chemistry, and the elucidation of chemical structures.
- develop competence in the application of common laboratory techniques in chemistry,
particularly those relevant to the measurement of drug structure and activity;
- in conjunction with Ch1001, to provide the background in key chemical concepts and
principles necessary for appropriate understanding of the pharmaceutics, medicinal
chemistry and pharmacology subjects in later years of the course.
Study Period 2
|Census Date 29-Aug-2019
||Assoc. Professor Michael Oelgemoeller
||Dr Murray Davies, Assoc. Professor Michael Oelgemoeller, Dr Mark Barnes, Professor Peter Junk.
- 39 hours lectures
- 20 hours tutorials - 2 h guided learning tutorials in weeks 3-13
- 30 hours practicals
||end of semester exam (60%); assignments (10%); laboratory work and reports (30%).
Minor variations might occur due to the continuous Subject quality improvement
process, and in case of
minor variation(s) in assessment details, the Subject Outline represents the latest