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CH3403 - Medicinal Chemistry and Pharmaceutical Analysis

Credit points: 3
Year: 2022
Student Contribution Band: Band 2
Administered by: College of Science and Engineering

This subject builds upon the fundamental concepts of chemistry introduced in the first year subjects. It deals with the key chemical concepts of medicinal/pharmaceutical chemistry and pharmacology, including the mechanisms of drug action and metabolism. The subject also introduces the principles of drug stability and basic mechanism of drug degradations. The importance of chemical analysis in relation to drug development, drug testing and quality control is examined. Specific topics to be covered include instrumental methods of analysis and structure determination of active pharmaceutical ingredients (API's), particularly NMR, chromatographic separation techniques (HPLC and GLC, thermal analysis methods (DSC and TGA) and Vibrational Spectroscopic techniques (FTIR and Raman spectroscopy). Pharmaceutical case studies are also covered as well as its application in a biomedical setting.

Learning Outcomes

  • employ medicinal chemistry and pharmacology principles in a biomedical setting;
  • describe mechanisms of drug metabolism and drug stability relevant to biomedical applications;
  • utilize spectroscopic techniques used in the quality control of pharmaceuticals or in a clinical setting;
  • explain polymorphism, the analytical techniques used to differentiate them, and its impact on drug activities;
  • describe modern purification techniques in pharmaceutical chemistry;
  • solve pharmaceutical analysis case studies in an industrial or clinical setting;
  • employ chemical laboratory techniques to synthesise and/or analyse pharmaceuticals and their formulations.

Subject Assessment

  • Written > Examination (centrally administered) - (55%) - Individual
  • Written > Test/Quiz 1 - (20%) - Individual
  • Practical assessment/practical skills demonstration:20% Class participation: 5% - (25%) - Individual.
Assumed
Knowledge:
First year Chemistry
Prerequisites: CH1001, CH1002
Inadmissible
Subject
Combinations:
PC2002, PC2203, CH2043

Availabilities

Townsville, Study Period 1, Mixed attendance
Census Date 24-Mar-2022
Face to face teaching (Guided Learning Sessions and Practicals on campus)
Workload expectations:

The student workload for this 3 credit point subject is approximately 130 hours.

  • 12 hours practicals
  • 12 hours workshops
  • 39 hours online interactive lectures
  • assessment and self-directed study

Note: Minor variations might occur due to the continuous Subject quality improvement process, and in case of minor variation(s) in assessment details, the Subject Outline represents the latest official information.