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CH3100 - Molecular Basis of Therapeutics 4

Credit points: 3
Year: 2019
Student Contribution Band: Band 2
Administered by: College of Science and Engineering

Available to students who are enrolled in the BPharm, BPharm IHCAP Program and the BPharm Honours Programs.

This subject will examine the medicinal chemistry relevant to the process of drug discovery and development as practised in the modern pharmaceutical industry. Building on the material covered in second year, it will develop in students a knowledge of the research tools which are applied in the drug discovery process. Topics in this subject may include: high throughput screening, computational chemistry and molecular modelling, QSAR, combinatorial synthesis techniques, pharmaceutical degradation and the use of natural products or derivatives thereof in pharmaceuticals.

Learning Outcomes

  • explain routes of pharmaceutical degradation and solve model problems on the kinetics of this process;
  • employ preparative techniques to synthesise model pharmaceuticals and undertake their analysis in a practical setting;
  • discuss modern strategies used in the drug discovery and development process;
  • assess the role chemical functionalities of a drug molecule and their changes have on its pharmacodynamics and pharmacokinetics;
  • identify natural products classes and explain their role in the drug discovery process.
Prerequisites: BC2014 and PC2002 and PC2004 and PC2006 and HS2401 and PC2001 and PC2003 and PC2201.


Townsville, Study Period 2, Internal
Census Date 29-Aug-2019
Coordinator: Dr Mark Robertson
Lecturers: Assoc. Professor Michael Oelgemoeller, Dr Mark Robertson.
Workload expectations:

The student workload for this 3 credit point subject is approximately 130 hours.

  • 36 hours lectures
  • 3 hours tutorials - 3 x 1 hour tutorials
  • 24 hours practicals - 6 x 4 hour pracs
  • assessment and self-directed study
Assessment: end of semester exam (70%); practicals (30%).

Note: Minor variations might occur due to the continuous Subject quality improvement process, and in case of minor variation(s) in assessment details, the Subject Outline represents the latest official information.