CH3040 - Advanced Medicinal Chemistry
|Student Contribution Band:
||College of Science and Engineering
This subject will examine the medicinal chemistry relevant to the process of drug
discovery and development as practised in the modern pharmaceutical industry. Building
on the material covered in second year, it will develop in students a knowledge of
the research tools which are applied in the drug discovery process. Topics in this
subject may include: high throughput screening, computational chemistry and molecular
modelling, QSAR, combinatorial synthesis techniques, pharmaceutical degradation and
the use of natural products or derivatives thereof in pharmaceuticals.
- explain routes of pharmaceutical degradation and solve model problems on the kinetics
of this process;
- employ preparative techniques to synthesise model pharmaceuticals and undertake their
analysis in a practical setting;
- discuss modern strategies used in the drug discovery and development process;
- assess the role chemical functionalities of a drug molecule and their changes have
on its pharmacodynamics and pharmacokinetics;
- identify natural products classes and explain their role in the drug discovery process.
- Invigilated > End of semester exam - (70%)
- Practicals - (30%).
||Prerequisites - CH1001, CH1002. Students are also recommended to have completed PC2002
Minor variations might occur due to the continuous Subject quality improvement process,
and in case
of minor variation(s) in assessment details, the Subject Outline represents the latest