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CH3040 - Advanced Medicinal Chemistry

Credit points: 3
Year: 2019
Student Contribution Band: Band
Administered by: College of Science and Engineering

This subject will examine the medicinal chemistry relevant to the process of drug discovery and development as practised in the modern pharmaceutical industry. Building on the material covered in second year, it will develop in students a knowledge of the research tools which are applied in the drug discovery process. Topics in this subject may include: high throughput screening, computational chemistry and molecular modelling, QSAR, combinatorial synthesis techniques, pharmaceutical degradation and the use of natural products or derivatives thereof in pharmaceuticals.

Learning Outcomes

  • explain routes of pharmaceutical degradation and solve model problems on the kinetics of this process;
  • employ preparative techniques to synthesise model pharmaceuticals and undertake their analysis in a practical setting;
  • discuss modern strategies used in the drug discovery and development process;
  • assess the role chemical functionalities of a drug molecule and their changes have on its pharmacodynamics and pharmacokinetics;
  • identify natural products classes and explain their role in the drug discovery process.
Prerequisites: Prerequisites - CH1001, CH1002. Students are also recommended to have completed PC2002 OR CH2043
Inadmissible
Subject
Combinations:
CH3100, CH3102

Availabilities

Townsville, Internal, Study Period 2
Census Date 29-Aug-2019
Coordinator: Dr Mark Robertson
Lecturers: Assoc. Professor Michael Oelgemoeller, Dr Mark Robertson.
Workload expectations:

The student workload for this 3 credit point subject is approximately 130 hours.

  • 36 hours on-campus > Lectures
  • 3 hours on-campus > Tutorials
  • 24 hours on-campus > Practicals
  • assessment and self-directed study
Assessment: end of semester exam (70%); practicals (30%).

Note: Minor variations might occur due to the continuous Subject quality improvement process, and in case of minor variation(s) in assessment details, the Subject Outline represents the latest official information.