CH2043 - Medicinal Chemistry and Pharmaceutical Analysis
|Student Contribution Band:
||College of Science and Engineering
This subject builds upon the fundamental concepts of chemistry introduced in the first
year subjects. It deals with the key chemical concepts of medicinal/pharmaceutical
chemistry and pharmacology, including the mechanisms of drug action and metabolism.
The subject also introduces the principles of drug stability and basic mechanism of
drug degradations. The importance of chemical analysis in relation to drug development,
drug testing and quality control is examined. Specific topics to be covered include
instrumental methods of analysis and structure determination of active pharmaceutical
ingredients (API's), particularly NMR, chromatographic separation techniques (HPLC
and GLC, thermal analysis methods (DSC and TGA) and Vibrational Spectroscopic techniques
(FTIR and Raman spectroscopy). Pharmaceutical case studies are also covered.
- explain the principles of medicinal chemistry and pharmacology for pharmaceutical
agents, including mechanisms of drug metabolism and drug stability;
- describe and apply spectroscopic techniques used in the quality control of pharmaceuticals,
in drug testing & development;
- explain polymorphism and the analytical techniques used to differentiate them;
- describe modern separation techniques in pharmaceutical chemistry;
- understand and solve pharmaceutical application case studies.
- end of semester exam (% - 60%)
- quizzes or tests (% - 10%)
- practicals (% - 30%).
|First year chemistry
Study Period 1
|Census Date 26-Mar-2020
||Assoc. Professor Michael Oelgemoeller
||Assoc. Professor Michael Oelgemoeller, Dr Mark Robertson, Professor Peter Junk.
The student workload for this
credit point subject is approximately
- 36 hours lectures
- 3 hours tutorials
- 12 hours practicals
- assessment and self-directed study
Minor variations might occur due to the continuous Subject quality improvement process,
and in case
of minor variation(s) in assessment details, the Subject Outline represents the latest