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CH2010 - Biological Chemistry

Credit points: 3
Year: 2012
Student Contribution Band: Band 4
Administered by: School of Pharmacy & Molecular Sciences

None

General Chemistry revision Acid/base and organic functional group chemistry. Natural Product Chemistry Extraction, chromatography, analysis, spectroscopy; terpenes, steroids, alkaloids, lignins. Bio-organic Chemistry Structure and function of carbohydrates, proteins and DNA; Disperse systems macromolecular colloids, emulsions. Bio-inorganic Chemistry Coordination complexes. Hemoglobin, Chlorophyll metalloenzymes. Photosynthesis : Rubisco and the C3 photosynthetic pathway. Enzymatic Chemistry The function of enzymes, inhibitors, cofactors, coenzymes and vitamins. Lipids and Membranes Fatty acids, complex lipids, lipid proteins, steroids, fluid mosaic membrane. Passive/active transport. Bioenergetics Catabolic and anabolic reactions. The metabolic role of ATP. Fatty acid synthesis. Glucogenesis. Glycolysis and the citric acid cycle. Electron Transport Oxidative phosphorylation. Shuttles. DNA Processes Replication, transcription and translation. Recombinant DNA and PCR. DNA microarrays. Oncogenes, Cancer drugs. Gene regulation. Signal transduction.

Learning Outcomes

  • develop an understanding of molecular processes involved in natural product chemistry and biochemistry;
  • survey of molecular techniques appropriate to working with natural products and biochemicals, with practical experience in the use of these methods;
  • to provide a general framework on the aspects of chemistry/ biochemistry that are important in the biological sciences.

Graduate Qualities

  • The ability to think critically, to analyse and evaluate claims, evidence and arguments;
  • The ability to adapt knowledge to new situations;
  • The ability to lead, manage and contribute effectively to teams;
  • The ability to speak and write logically, clearly and creatively;
  • The acquisition of coherent and disciplined sets of skills, knowledge, values and professional ethics from at least one discipline area;
  • The ability to reflect on and evaluate learning, and to learn independently in a self directed manner.
Prerequisites: (CH1011 AND CH1012) OR (CH1001 AND CH1002)
Inadmissible
Subject
Combinations:
BM1000 CH1010

Availabilities

Cairns, Study Period 1, Internal
Census Date 22-Mar-2012
Coord/Lect: Assoc. Professor Michael Liddell.
Workload expectations:
  • 36 hours lectures
  • 10 hours tutorials
  • 30 hours practicals
  • 10 hours - LearnJCU modules.
Assessment: end of semester exam (35% - 55%); quizzes or tests (25% - 45%); essays (5% - 15%); marks for practical exercises (15% - 25%).
Special Assessment Requirements: Practical component: students will fail the course if they miss 3 or more practicals without a valid reason (generally medical certificates will be required).

Note: Minor variations might occur due to the continuous Subject quality improvement process, and in case of minor variation(s) in assessment details, the Subject Outline represents the latest official information.