CH2010 - Biological Chemistry
|Student Contribution Band:
||College of Science and Engineering
General Chemistry revision Acid/base and organic functional group chemistry.
Natural Product Chemistry Extraction, chromatography, analysis, spectroscopy;
terpenes, steroids, alkaloids, lignins. Bio-organic Chemistry Structure and
function of carbohydrates, proteins and DNA; Disperse systems macromolecular
colloids, emulsions. Bio-inorganic Chemistry Coordination complexes. Hemoglobin,
Chlorophyll metalloenzymes. Photosynthesis : Rubisco and the C3 photosynthetic pathway.
Enzymatic Chemistry The function of enzymes, inhibitors, cofactors, coenzymes
and vitamins. Lipids and Membranes Fatty acids, complex lipids, lipid proteins,
steroids, fluid mosaic membrane. Passive/active transport. Bioenergetics Catabolic
and anabolic reactions. The metabolic role of ATP. Fatty acid synthesis. Glucogenesis.
Glycolysis and the citric acid cycle. Electron Transport Oxidative phosphorylation.
Shuttles. DNA Processes Replication, transcription and translation. Recombinant
DNA and PCR. DNA microarrays. Oncogenes, Cancer drugs. Gene regulation. Signal transduction.
- have developed an understanding of molecular processes involved in natural product
chemistry and biochemistry;
- have surveyed the use of molecular techniques appropriate to working with natural
products and biochemicals, with practical experience in the use of many of these methods;
- been provided with a general theoretical framework on the aspects of chemistry/biochemistry
that are important in the biological sciences;
- be able to express scientific ideas using written communication skills;
- be able to interpret and analyze data, generated from experimental or theoretical
- Invigilated > End of semester exam - (55%)
- Invigilated > Other exams - (18%)
- Non-Invigilated > Essays - (10%)
- Marks for practical exercises - (17%).
Special Assessment Requirements
Practical component: students will fail the course if they miss 2 or more practicals
without a valid reason (generally medical certificates will be required).
||(CH1011 OR CH1001)
Minor variations might occur due to the continuous Subject quality improvement process,
and in case
of minor variation(s) in assessment details, the Subject Outline represents the latest