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CH2010 - Biological Chemistry

[Not offered in 2020]

Credit points: 3
Year: 2020
Student Contribution Band: Band 2
Administered by: College of Science and Engineering


General Chemistry revision Acid/base and organic functional group chemistry. Natural Product Chemistry Extraction, chromatography, analysis, spectroscopy; terpenes, steroids, alkaloids, lignins. Bio-organic Chemistry Structure and function of carbohydrates, proteins and DNA; Disperse systems macromolecular colloids, emulsions. Bio-inorganic Chemistry Coordination complexes. Hemoglobin, Chlorophyll metalloenzymes. Photosynthesis : Rubisco and the C3 photosynthetic pathway. Enzymatic Chemistry The function of enzymes, inhibitors, cofactors, coenzymes and vitamins. Lipids and Membranes Fatty acids, complex lipids, lipid proteins, steroids, fluid mosaic membrane. Passive/active transport. Bioenergetics Catabolic and anabolic reactions. The metabolic role of ATP. Fatty acid synthesis. Glucogenesis. Glycolysis and the citric acid cycle. Electron Transport Oxidative phosphorylation. Shuttles. DNA Processes Replication, transcription and translation. Recombinant DNA and PCR. DNA microarrays. Oncogenes, Cancer drugs. Gene regulation. Signal transduction.

Learning Outcomes

  • have developed an understanding of molecular processes involved in natural product chemistry and biochemistry;
  • have surveyed the use of molecular techniques appropriate to working with natural products and biochemicals, with practical experience in the use of many of these methods;
  • been provided with a general theoretical framework on the aspects of chemistry/biochemistry that are important in the biological sciences;
  • be able to express scientific ideas using written communication skills;
  • be able to interpret and analyze data, generated from experimental or theoretical problems.

Subject Assessment

  • Invigilated > End of semester exam - (55%)
  • Invigilated > Other exams - (18%)
  • Non-Invigilated > Essays - (10%)
  • Marks for practical exercises - (17%).

Special Assessment Requirements

Practical component: students will fail the course if they miss 2 or more practicals without a valid reason (generally medical certificates will be required).

Prerequisites: (CH1011 OR CH1001)
BM1000 CH1010

Note: Minor variations might occur due to the continuous Subject quality improvement process, and in case of minor variation(s) in assessment details, the Subject Outline represents the latest official information.