BC3102 - Molecular Basis of Disease
Credit points: |
3 |
Year: |
2023 |
Student Contribution Band: |
Band
2 |
Administered by: |
College of Public Health, Medical and Vet Sciences |
For students who do not have the required pre-requisites, please seek advice from
the Discipline Academic Advisor to enrol
This subject builds on the principles and concepts introduced in BC2013 and BC2024
and focuses on how eukaryotic cells are regulated at the molecular and genetic level.
Topics covered include intracellular structures, signal transduction, protein sorting
and translocation, the cytoskeleton, the cell cycle, apoptosis, molecular immunology
and the molecular biology of cancer. Advanced cell biology is important to a wide
range of current biomedical and genetic research because it describes much of the
biochemical basis for modern treatment and prophylaxis approaches. The lectures and
practical sessions of this subject are focused on providing a background in molecular
biomedicine to compete effectively in the job market. The first half of semester covers
the structures and biochemistry of basic cell functions (division, death, movement,
production and responsiveness) while the second half integrates this knowledge to
develop a working understanding of the molecular bases of four complex biological
systems: tumour biology, disease, immune responses to foreign proteins (allergies)
and to infectious diseases (parasites).The subject concludes with a look to the past
leading to emerging technologies and their impact on the field of biomedical science.
Learning Outcomes
- Demonstrate conceptual understanding relating to modern molecular biology;
- Develop laboratory skills in the manipulation and analysis of cells and cellular biomolecules;
- Demonstrate proficiency in literacy, numeracy, critical thinking and scientific process;
- Source, synthesise and evaluate reliable scientific information with independence;
- Integrate knowledge of the molecular bases of cellular processes into knowledge of
basic cell functions and the ways they are coordinated within mammals (including humans)
to produce phenotypes (e.g. disease).
Subject Assessment
- Written > Examination (centrally administered) - (60%) - Individual
- Written > Test/Quiz 1 - (10%) - Individual
- Written > Essay (including multi-draft) 1 - (20%) - Individual
- Performance/Practice/Product > Practical assessment/practical skills demonstration - (10%) - Individual.
Special Assessment Requirements
Participate in and complete all assessment tasks in the practical classes. Attend
the mid-semester test; Submit two graded assignments; Attend the final exam; and Achieve
a total aggregate score of 50% or more across the sum of assessment items. Students
must pass both on-course and exam assessments, i.e 50% pass mark for both the aggregate
on-course assessments as well as the final exam.
Prerequisites: |
BC2013 AND BC2024 |
Inadmissible Subject Combinations:
|
BC3020 BC5102 GG3102 |
Availabilities
|
Townsville,
Study Period 1,
Internal
|
Census Date 23-Mar-2023 |
Coordinator: |
Dr Margaret Jordan, Professor David Whitmore |
Lecturers:
|
Dr Margaret Jordan, Professor Ludwig Lopata, Assoc. Professor Lionel Hebbard, Dr Sacha Jensen. |
Workload expectations: |
The student workload for this
3
credit point subject is approximately
130 hours.
- 32 hours lectures
- 4 hours tutorials
- 20 hours specialised
- assessment and self-directed study
|
|
|
Note:
Minor variations might occur due to the continuous Subject quality improvement process,
and in case
of minor variation(s) in assessment details, the Subject Outline represents the latest
official information.